recombination frequency

To disrupt a gene by homologous integration in Aspergillus fumigatus, transformation via the spheroplast method has been most widely used; this is a laborious and time-consuming method, and the homologous recombination frequency can be relatively low.

用原生质体通过同源重组来打断基因的方法曾经被广泛运用，但此方法费时、费力，而且其同源重组的频率也比较低。

High Frequency of Homologous Recombination in the Genome of Modified Vaccinia Virus Ankara Strain ( MVA)

修饰的痘苗病毒安卡拉株（MVA）基因组中高频的同源重组（英文）

High Frequency of Homologous Recombination in the Genome of Modified Vaccinia Virus Ankara Strain ( MVA )

修饰的痘苗病毒安卡拉株(MVA)基因组中高频的同源重组 ( 英文 )

But the frequency of recombination was very low ( 0.1%-1%) and it limited further application of the baculovirus expression vector system ( BEVS).

但由于重组病毒产生的比例很低（通常只有01%～1%），成为制约该系统应用的技术瓶颈。